Cannabidiol, also known as CBD, is the second most abundant compound in cannabis sativa, behind THC.
It’s important to note that cannabidiol has always been part of the synergistic effects of cannabis. The importance of CBD has just been minimized by the focus on psychoactivity of the marijuana plant. For a long time cannabis was bred to maximize THC content, to the exclusion of medicinal benefits offered by other cannabinoid compounds. That’s changing now, and clearly this is a substance that has a lot to offer on many levels.
Cannabis Sativa can be a confusing topic for the average consumer because variations of the same plant can be either considered marijuana (a controlled substance that currently remains illegal by federal law) or hemp (a plant that’s extracts and products can legally be sold in all 50 States.)
It can be hard to understand, but the difference between Hemp and Marijuana is only the concentration of THC, the psychoactive component of cannabis sativa plants.
Any product containing less than .3% THC is legally a “hemp” product. Hemp products might be made from the whole plant (leaves, stems, seeds) of an industrial crop grown for rope making or it might be a carefully cultivated budding flower bred specifically for its high concentrations of CBD.
The best CBD products come from the flowering buds of specially grown CBD help.
An abundance of peer reviewed scientific literature supports alternative health practitioners who claim that CBD oil can treat pain, inflammation, discomfort and disease.
CBD oil is the latest trend to come from the marijuana industry. Patients and consumers are happy to find safe alternative methods to care for various health issues. CBD patrons have greater control, enjoyment, and freedom over their medication than many prescription drug users.
Unlike medical marijuana, anyone can buy CBD over the counter without a prescription.
Just because it’s easier to get your hands on doesn’t mean it’s less effective. Clinical research shows that CBD offers more powerful anti-inflammatory and immune system modulating effects than THC, and at lower doses. (3.)
CBD oil won’t get you high – but it certainly works wonders for a wide array of medical problems.
How Does CBD Work?
In the mid 90’s Israeli researchers determined that humans have a natural biological system of cannabinoid receptors and special neurotransmitters that bind to them. This biological system is called the endocannabinoid system and it is spread throughout your entire body, including your skin.
The two most well known natural cannabinoid receptors in the human body are commonly referred to as CB1 and CB1.
CB1 receptors are commonly found in the brain and nervous system, while CB2 receptors are found throughout the gastrointestinal system and the immune system.
The six known endocannabinoids that appear naturally in our bodies are arachidonoylethanolamine (anandamide), 2-arachidonoyl glycerol (2-AG), 2-arachidonyl glyceryl ether (noladin ether), virodhamine, and N-arachidonoyl-dopamine (NADA) 
Our cannabinoid receptors don’t just get us high – they are involved in a variety of physiological processes including appetite, pain-sensation, immune system modulation, mood, and memory.
THC, the psychoactive component of marijuana, is known for it’s ability to bind to CB1 receptors and produce mind-altering effects.
Unlike THC, cannabidiol (CBD) does not bind to your cannabinoid receptors. Instead cannabidiol is an endocannabinoid modulator. In other words, when given chronically, it actually strengthens your natural endocannabinoid system, which is fundamentally a homeostatic regulator.
To clarify that, homeostasis means “a state of balance.” Many diseases interfere with a balance in a given system and correcting that imbalance will improve the condition. The endocannabinoid system runs through almost every organ in the human body. This is what makes cannabidiol oil such a versatile medicine.
If there’s too much activity in the endocannabinoid system, homeostasis requires that it be brought back down. If there’s too little, it has to be increased. Cannabidiol oil can do that for us without any major side effects.
Why Put CBD In Oil?
CBD is a “lipid soluble” compound, which means it dissolves in oil rather than water, making oil tinctures the easiest and best carrier method and mode of delivery for CBD.
Our intestinal lymphatic systems are really good at absorbing oil and fats, especially medium chain triglycerides which have a smaller particle size and are easier to digest and absorb.
A carrier oil helps medicines absorb into your system them through the lymphatic system and into the blood stream.
Studies show that carrier oil increases the bioavailability of CBD three fold 
In one study, researchers from the University of Nottingham looked into cannabidiol (CBD) for the treatment of spasticity in multiple sclerosis (MS) patients and to alleviate nausea and vomiting associated with chemotherapy in cancer patients.
This study from he University of Nottingham found that CBD oil was readily absorbed by the lymphatic system and concluded that “administering cannabinoids in oil has the potential to be a therapeutic approach to improve the treatment of MS, or indeed other autoimmune disorders.” 
Conditions CBD Oil Can Help
Seizure disorders like epilepsy are the most well-known reason to supplement with CBD oil. Charlotte’s Web brand CBD Hemp was cultivated to help a child named Charlotte suppress her seizures. But just as Charlotte’s Web isn’t the only CBD Hemp Oil on the market (it’s just one of the most expensive) seizure disorder’s are not the only reason to take this miracle wellness tonic.
More and more disorders are starting to be classified as “Clinical Endocannabinoid Deficiency”  including migraine, fibromyalgia, and irritable bowel syndrome.
Cannabinoids can block spinal, peripheral and gastrointestional mechanisms that promote pain in headache, fibromyalgia, irritable bowel syndrome and muscle spasm. CBD oil can provide relief from inflammation and mitigate the effects of autoimmune disorders.
Here are some other interesting findings on the benefits of cannabidiol CBD oil:
Alzheimers – CBD oil was shown to help clear the brain of beta-amyloid plaques that cause dementia and alzheimers
Chronic Pain – Studies have shown that THC and CBD oil are more effective when administered together than either are apart, and the study further indicates that CBD alone is a more potent pain remedy than THC alone.
Insomnia and anxiety – shown to be useful in pediatric cases of PTSD (5)
Parkinson’s Disease – there are several studies showing that CBD oil can mitigate the symptoms of parkinsons’s (6)
Cancer – not only can CBD lower inflammation and alleviate nausea and vomiting in people suffering from cancer but studies also show that CBD can induce apoptosis (the process by which our bodies kill and remove cancer cells) and actually shrink tumors.
Where to Buy CBD Oil
I love this product – but Amazon currently does not allow vendors to sell CBD Hemp oil. You know I’m serious about this one because, as an amazon affiliate marketer, I usually make a small amount of money when my readers make amazon purchases. I don’t want that on my conscience.
DO NOT BUY IT ON AMAZON
I ordered 4 different “hemp oils” from Amazon sellers and every single one of them was fake. I think most of them were just overpriced hemp seed oil in small bottles. Hemp seed oil doesn’t contain any CBD or cannabinoids at all. One of the products I received from Amazon tasted right but made me horribly stomach sick.
This is an entirely unregulated market and it’s important to find a vendor you can trust.
My absolute favorite brand of Full Spectrum CBD Hemp Oil is Immortal Tortoise. I got a sample from them at a health trade show and it tasted wonderful and melted the ache of walking around in high heels instantly off of my feet and back. Their product is top-notch and they offer the 3rd party lab tests to prove it.
They also offer extremely competitive pricing compared to the other brands on the market.
You can order the best CBD products on the market at
My second favorite brand is Bluebird Botanicals. Their product does not taste or smell as good as the Immortal Tortoise brand but it definitely works. Although they claim to be 3rd party lab tested, unlike Immortal Tortoise they don’t actually publish their lab results right on their website. They also offer competitive prices compared to a lot of brands on the market, and they have a really nice website.
My third favorite brand of CBD Oil is Elixinol. In my opinion they are way overpriced for a product that is somewhat lower quality than Immortal Tortoise. However, they offer a much wider selection of products in terms of flavor and even their plain CBD tincture has a better flavor than bluebird botanicals.
My advice is to buy CBD oil online from a retailer that sources their hemp from colorado (see my three selections above.)
I have tried maybe half a doze “CBD” products I found on the shelves in head shops and vitamin stores in my state (PA) and (just like my amazon purchases) they were all fake. Some of them claimed to only have CBD and a carrier oil in the bottle but clearly contained flavoring and sweetener, and had no benefit whatsoever.
Stick to well reviewed trusted retailers of colorado sourced CBD Hemp Oil who offer 3rd Party Lab results.
 Sci Rep. 2017 Nov 6;7(1):14542.
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation.
Zgair A, Lee JB, et al
 American J of Transl Research 2016; 8(8): 3448–3459.
Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines
Atheer Zgair, Jonathan CM Wong, et al
 Scientific Reports. 2017; 7: 14542. Published online 2017 Nov 6.
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation
Atheer Zgair, Jong Bong Lee, Jonathan C. M. Wong, et al
 Shoemaker JL, Ruckle MB, Mayeux PR, Prather PL (Nov 2005). “Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptors”. The Journal of Pharmacology and Experimental Therapeutics. 315 (2): 828–38.
 Published online 2016 Oct 12. The Permanente journal
Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report
Scott Shannon, MD, ABIHM
 Journal of Psychopharmacology. 2008 Sept. Volume: 23 issue: 8, page(s): 979-983
Cannabidiol for the treatment of psychosis in Parkinson’s disease
AW Zuardi, Jas Crippa, JEC Hallak, JP Pinto, MHN Chagas, GGR Rodrigues, SM Dursun, V. Tumas
 Neuro Endocrinol Lett. 2014;35(3):198-201.
Clinical endocannabinoid deficiency (CECD) revisited: can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
Smith SC, Wagner MS.